Cannot start Microsoft Office Outlook

Question

Hi,

I’ve already restarted my Outlook several times but the following error message still recurs. What should I do?

[Cannot start Microsoft Office Outlook. Cannot open the Outlook window. The set of folders cannot be opened. “exited without properly closing your Outlook data file ’C:\Users\…….’

’Microsoft Office Outlook’ must be restarted. If this error message recurs, contact support for” for assistance.]

Best regards,

KN

Answer 1

Hi Kathy Ng,

Welcome to our forum!

Based on your description, we understand that the issue has occurred when opening Outlook client. About this issue, please try below methods and check if it helps.

1. Recreate the Outlook email profile.:

Go to the Windows search bar and type regedit. This will launch the Registry Editor. Then, navigate to Computer\HKEY_CURRENT_USER\SOFTWARE\Microsoft\Office\16.0\Outlook\Profiles (Outlook 2019,2016) Restart the computer. Relaunch Outlook and recreate your email profile.

Open Outlook in safe mode and disable all add-ins. If Outlook works well in safe mode, then this issue is caused by add-ins. To confirm which add-ins is the cause of this issue, you can re-enable add-ins one by one until this issue occurs again. To open Outlook in safe mode, right-click the Start button > click Run > type Outlook.exe /safe, and click OK.

For additional information, you can refer to I can’t start Microsoft Outlook or receive the error “Cannot start Microsoft Outlook. Cannot open the Outlook Window” - Microsoft Support 

---

If the answer is helpful, please click "Accept Answer" and kindly upvote it. If you have extra questions about this answer, please click "Comment".

Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.