Dear alyson lie,
Thank you for your patient update.
As per your description, this issue occurred in new profile and PowerPoint online without the same issue, and the URL changed. This issue may be due to some conflict between the PowerPoint client and YuTube. I'm afraid this issue needs to be investigated from the backend side via remote assistance and collect the background logs. As this Forum community has limited resources, the backend support team there has more permission than us, they have more resources to investigate the issue from the backend, they have Escalate channel to escalate your issue to check more and collect log reports for the root cause.
For your reference: Get support - Microsoft 365 admin | Microsoft Learn
In the meanwhile, I also recommend you report this issue to Youtube Support.
And also send feedback from within PowerPoint > Help menu > Feedback > Report a problem. Feedback submit by this way directly goes to the related team. This is the way to let the developers know this issue and help to investigate it.
Thank you for your patience and understanding.
Sincerely,
Claire | Microsoft Community Moderator