We can't install - a message that I always get when starting OfficeSetup for Office 365

You may create a new Windows user account and perform a clean install of the latest Office 365 desktop application to see whether the problem still occurs.

Moreover, if your IT department manages Windows account creation, then I would suggest you contact them for further assistance.

Hello @Mahmoud Abdelkader,  

Thank you for posting your valuable question on Microsoft Q&A forum.   

To help us provide the most accurate and effective solution for the issue, could you share a bit more detail about your setup:

• Are you signed in to with a personal account (e.g., Outlook.com, Gmail) or a work/school account linked to your organization’s domain? 
• Is your device provide and managed by your organization or this is a personal device? 
• Do you have admin rights on this device?” 
• What type of Microsoft 365 subscription do you have? (Business, Enterprise, Education, Personal) 
• Where did you download the Office installer from? (Microsoft 365 portal, Volume Licensing Service Center, or elsewhere) 
• Do you currently have any version of Office installed? If yes, which version and update channel? 
• Do you know which update channel your organization uses? (Current Channel, Monthly Enterprise Channel, Semi-Annual Channel) 
• Are you using the standard installer or the Office Deployment Tool (ODT)? 

This additional context will help us understand your environment and the steps already taken so we can tailor the guidance to resolve the issue effectively. 
In the meantime, you can refer to these official documents from Microsoft: 

Troubleshooting Office installation errors - Microsoft 365 Apps | Microsoft Learn 

Download, install, or reinstall Microsoft 365 or Office 2024 on a PC or Mac - Microsoft Support 

I apologize for not jumping straight to a solution. I want to avoid suggesting anything that might be inaccurate or unhelpful. Once I have the details above, I’ll be able to assist you more effectively and guide you toward the right resolution. 

Looking forward to your response so we can get this sorted out for you together!

If you have extra questions about this answer, please click "Comment". 

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