Hello @IDN Dev
As of now, you can use Azure AD MFA for secondary authentication only with web applications which are federated with ADFS. In that case, ADFS can do the 1st factor authentication with on-premises Active Directory and for 2nd Factor authentication, requests can be forwarded to Azure AD MFA service. For step by step instructions on how to configure ADFS to use Azure MFA for 2nd factor authentication, you can refer to this document: https://learn.microsoft.com/en-us/windows-server/identity/ad-fs/operations/configure-ad-fs-and-azure-mfa
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