Hi @Gain, S. (Stephan),
You can try this registry key to block all com add-ins (If RestrictToList is set to 1, but you do not enable any add-ins using the List of managed add-ins policy, all COM add-ins are disabled.):
Key: HKEY_CURRENT_USER\Software\Policies\Microsoft\Office\x.0<application>\Resiliency
DWORD: RestrictToList
Value: 1
You can get the information from this article:
https://learn.microsoft.com/en-us/microsoft-365/troubleshoot/group-policy/office-add-in-not-loaded
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