Hi @ Ardan Zaki ,
I have resolved the issue
Great to know that you've already got of a solution and really appreciate it for your sharing!
By the way, since the Microsoft Q&A community has a policy that "The question author cannot accept their own answer. They can only accept answers by others.". and according to the scenario introduced here: Answering your own questions on Microsoft Q&A, I would make a brief summary of this thread:
[HRESULT:80070005 in ECP after install KB5023697 (windows server 2016)]
Issue Symptom:
After installing the latest CU for Windows Server 2016 (KB5023697) on the Exchange server, cannot access the server through the ECP external URL.
The solution:
1.Check that TLS 1.2 is enabled on all servers, and disable TLS 1.0 and 1.1 .
2.Check whether the certificate binding in IIS is correct and check the authentication of each site.
You could click the "Accept Answer" button for this summary to close this thread, and this can make it easier for other community member's to see the useful information when reading this thread. Thanks for your understanding!