Hi @ChaitanyaNaykodi-MSFT , I followed the process from the issue and it doesn't have anything to do with browser support.
So I get the same warning as the user from the issue.
"To enable Authentication / Authorization please ensure all your custom domains have corresponding SSL bindings .net version is configured to "4.5" and manage pipeline mode is set to "Integrated".
I managed to save the auth-settings, but I get CORS errors and there is something not working right. I created another azure functions app, and it worked without problems. Could it be that because it is grayed out, something in the authentication settings are not working correctly?