Hi,
I guess your configuration service jobs / stored procedures are failing to execute.
- Ensure your SQL is up and running and is not overloaded.
- Verify from when this issue is occurring and revert all the changes you did from then.
- Delete unwanted management packs which you do not want.
- Try to reduce the batch size of the SCOM configuration reducing it from the config file on all the MS as in the below link:
Configuration isn't updated and event ID 29181 is logged in System Center Operations Manager