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Yes, it recommended to disable TLS 1.0 and 1.1 and only enable TLS 1.2 for security reasons. TLS 1.0 and 1.1 are considered less secure and have known vulnerabilities that can be exploited. Once you've disabled the older protocols, restarting your VMs would be a good step to apply the changes.
Additionally:
You can check if your clients and applications support TLS 1.2 by testing them against a TLS 1.2-only endpoint. If your clients and applications are able to connect to the endpoint successfully, then they support TLS 1.2, and you can safely disable TLS 1.0 and 1.1
To maintain a secure environment, it is advisable to disable TLS 1.0 and 1.1 and ensure that all clients and servers are configured to use TLS 1.2 or later.
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