Hi @Michele ,
Installing Exchange 2016 on Windows 2019 is not supported.
https://learn.microsoft.com/en-us/exchange/plan-and-deploy/system-requirements?view=exchserver-2016#supported-operating-systems-for-exchange-2016
Please find the below reference for the pre-requisites for installing the latest Exchange 2016 CU in the windows 2016
https://learn.microsoft.com/en-us/exchange/plan-and-deploy/prerequisites?view=exchserver-2016#exchange-2016-prerequisites-for-preparing-active-directory
If the above suggestion helps, please click on "Accept Answer" and upvote it.