MP control Manager detected user service is not responding to HTTP requests (error 403, 404, 500)

Question

I'm experiencing issue with SCCM CB 2002 where the MP status shown as red warning with the error messages below are being thrown randomly in the logs

MP control Manager detected user service is not responding to HTTP requests. The http error is 403
MP control Manager detected user service is not responding to HTTP requests. The http error is 404
MP control Manager detected user service is not responding to HTTP requests. The http error is 500

Previously everything was working fine until our we made changes to the registry to disable protocols below TLS 1.2

We have followed all the steps outlined here : https://learn.microsoft.com/en-US/mem/configmgr/core/plan-design/security/enable-tls-1-2 to ensure it can work with TLS 1.2 but still no luck

We even tried rollback the changes by re-adding registry to enable TLS1.1 and other older protocols but still the error persists.

Kindly advise what else that we can do.

SCCM CB 2002 installed on Windows Server 2016 (MP + WSUS role in the same server) and SQL server is external using SQL Server 2019.