Hi @Nicholas Parry ,
Welcome to our forum!
Your message is larger than the size limit for messages. Please make it smaller and try sending it again.
From the error report, this issue may occur due to the attachment limits. Generally, there are different attachment limits between mail providers, for example, if you are an Office 365 for business user, the default attachment size limits is 150MB for Outlook client, 35MB for Outlook Web App.
May I know which mailbox you are using? If you are using an Exchange account, please confirm that the attachment size with your Exchange Administrator.
If that attachment size is more than a limit as Microsoft defined, to workaround it, you may compress the file or upload the file/document to oneDrive then share the link in the email.
More information you can refer to in the link below: Send large files with Outlook
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