Dear Kts123,
Thanks for providing the detailed information for our troubleshooting.
I do a test and it seems that I can't reproduce such an issue in our environment. Based on the article, the maximum size of each individual uploaded file is 250 GB. As the issue happens in multiple libraries in your environment, sorry for the inconvenience the issue caused and I'm afraid that it may be a default Upload option issue in your environment which may need to be involved with some logs from your side with our related team. I kindly suggest you contact the administrator in your company and open a support ticket to our related team as soon as possible so that they can help you further.
Meanwhile, I'd like you to try uploading files with the OneDrive sync client to see if you can upload such files. If yes, I suggest you use it as a current workaround.
To help you simplify the process of opening the support ticket, I'd like to summarize the issue as follows.
Issue Symptom:
====================
When uploading the files whose size is more than 92MB onto the OneDrive for Business , the error message "error in the application" appears.
Issue Environment:
====================
SharePoint Online and the OneDrive for Business library
Possible Workaround:
====================
Upload files with the OneDrive sync client
@William and Dawn, as you are experiencing the same error message when uploading the files of different sizes which don't reach the SharePoint Online upload limit onto SharePoint Online, I think that the issues you are experiencing may be an unexpected behavior and also need some logs' analysis with our related team further. Please contact the administrators in your organizations and open a support ticket to our related team as soon as possible for further investigation. Currently also welcome to try the OneDrive for Business sync client to see if you can upload the files.
Sorry for that our category may have limited resources to contact our related team directly.
Thanks for your understanding and hope that the issue can be fixed soon in your environments.
Cliff