Hi @DutchIvan
Check your policies with Cloud App Security:
1) Go to https://portal.cloudappsecurity.com/
2) Go to Control > Policies
3) Open the following policies:
4) Check your Governance actions (and I'd recommend to uncheck the following unless you want this type of behaviour to continue disrupting your users):
Note: If you have a tight security policy, keep these checked, but I happen to have the same thing going on and if this is checked off it is creating a kind of DoS (Denial of Service) attack.
If this is helpful please accept answer.